Working Experience

Jan. 2023～Now  Jiangxi Science and Technology Normal University  Associate Professor

Jul. 2015～Dec. 2022  Jiangxi Science and Technology Normal University  Lecturer

Education Background

Sep. 2008～Jul. 2015  Biochemistry and Molecular Biology China Agriculture University   Doctor of Science

Sep. 2002～Jul. 2006 Bioscience  Fudan University  Bachelor of Science

Research Field

1、Design, synthesis, and application of small molecule fluorescent probes

2、Research on the synthesis and regulation mechanism of secondary metabolites in Fungi

Research Achievements

Mainly research on the design, synthesis, and application of small molecule fluorescent probes and the synthesis and regulation mechanism of secondary metabolites in Fungi. In recent years, she has presided 3 provincial-level projects and 1 horizontal project as the project leader. She also participated in a number of national natural science foundation projects and provincial-level projects as a key member. At present, she published more than 20 SCI papers as the first corresponding author.

References

1、Wenbin Yu, Zhiwei Ouyang, Yufei Zhang, Yi Lu, Changhe Wei, Yayi Tu*, Bin He*. Research progress on the artificial intelligence applications in food safety and quality management, Trends in Food Science & Technology, 2025, 156, 104855.

2、Jianning Dong, Zixing Ye, Yayi Tu*, Congbin Fan*. A novel NIR fluorescent probe targeting mitochondria for the detection of Cys using benzothiocarbonate recognition site, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 325, 125169.

3、Wenbin Yu, Yufei Zhang, Yi Lu, Zhiwei Ouyang, Jiahua Peng, Yayi Tu*, Bin He*. Recent research on the bioactivity of polyphenols derived from edible fungi and their potential in chronic disease prevention, Journal of Functional Foods, 2025, 124, 106627.

4、Wenbin Yu, Zeying Zhao, Yufei Zhang, Yayi Tu*, Bin He*. AozC, a zn(II)2Cys6 transcription factor, negatively regulates salt tolerance in Aspergillus oryzae by controlling fatty acid biosynthesis, Microbial Cell Factories, 2025, 24, 10.

5、Wenbin Yu, Yufei Zhang, Lihua Yao, Jiahua Peng, Yayi Tu*, Bin He*. Research progress on the prevention of tumor by fungal polysaccharides, Trends in Food Science & Technology, 2024, 147, 104422.

6、Yufei Zhang, Wenbin Yu, Yi Lu, Yichuan Wu, Zhiwei Ouyang, Yayi Tu*, Bin He*. Epigenetic regulation of fungal secondary metabolism, Journal of Fungi, 2024, 10, 648.

7、Wenbin Yu, Yufei Zhang, Zhiwei Ouyang, Yayi Tu*, Bin He*. The molecular regulation of microbial metabolism, Frontiers in Cell and Developmental Biology, 2024, 12, 1458625.

8、 Wenbin Yu, Zeying Zhao, Bin Zeng, Yayi Tu*, Bin He*. Alanine supplementation enhancing cordycepin production in Cordyceps militaris via upregulation of Cns2 and Cns3 genes expression levels, Journal of Food and Drug Analysis, 2024, 32, 589-602.

9、Wenbin Yu, Rongqiang Pei, Yufei Zhang, Yayi Tu*, Bin He*. Light regulation of secondary metabolism in fungi, Journal of Biological Engineering, 2023, 17, 57.

10、Jianning Dong, Guowei Lu, Bin He, Yayi Tu*, Congbin Fan*. A novel NIR fluorescent probe for monitoring cysteine in mitochondria of living cells, Arabian Journal of Chemistry, 2023, 16 (6), 104765.

11、Wenbin Yu, Rongqiang Pei, Jingyi Zhou, Bin Zeng, Yayi Tu*, Bin He*. Molecular regulation of fungal secondary metabolism, World Journal of Microbiology and Biotechnology, 2023, 39: 204.

12、Rutao Liang, Xinyue Luo, Yanqing Luo, Fangfang Liu, Zhongyu Hu, Zhenhua Xiong, Yayi Tu*, Congbin Fan*. A highly selective and sensitive fluorescent probe for Zn2+ based on diarylethene with a thienyl hydrazide unit, Journal of Photochemistry and Photobiology A-Chemistry, 2023, 445, 115107.

13、Jianning Dong, Yanhua Wang, Congbin Fan, Yayi Tu*, Shouzhi Pu*. Chalcone dye-based fluorescent probe for selective and specific detection of cysteine in lysosomes of living cells, Dyes and Pigments, 2023, 210, 110994.

14、Guowei Lu, Jianning Dong, Congbin Fan, Yayi Tu*, Shouzhi Pu*. A coumarin-based fluorescent probe for specific detection of cysteine in the lysosome of living cells, Bioorganic Chemistry, 2022, 119, 105558.

15、Jianning Dong, Guowei Lu, Yayi Tu*, Congbin Fan*. Recent research progress of red-emitting/nearinfrared fluorescent probes for biothiols, New Journal of Chemistry, 2022, 46, 10995-11020.

16、Yanhua Wang, Guowei Lu, Yayi Tu*, Shouzhi Pu*. A turn-on fluorescent probe for the discrimination of Cys/Hcy and GSH with dual emission signals, Journal of Fluorescence, 2021, 31, 599-607.

17、Xufen Song, Yayi Tu*, Renjie Wang, Shouzhi Pu*. A lysosome-targetable fluorescent probe for simultaneous detection and discrimination of Cys/Hcy and GSH by dual channels, Dyes and Pigments, 2020, 177, 108270.

18、Lihui Zhai, Yayi Tu*, Zhanglin Shi, Shouzhi Pu*. A colorimetric and fluorescent chemosensor based on diarylethene for simultaneous detection and discrimination of biothiols, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 218, 171-177.

19、Lihui Zhai, Zhanglin Shi, Yayi Tu*, Shouzhi Pu*. A dual emission fluorescent probe enables simultaneous detection and discrimination of Cys/Hcy and GSH and its application in cell imaging, Dyes and Pigments, 2019, 165, 164-171.

20、Zhanglin Shi, Yayi Tu*, Renjie Wang, Gang Liu, Shouzhi Pu*. Highly sensitive and selective turn-on fluorescent sensor for dual recognition of Cu2+ and CN- based on a methylquinoline derivative, Dyes and Pigments, 2018, 149, 764-773.