Educational background

September 2013-June 2019 Lanzhou University, PhD (Organic Chemistry)

September 2009 -June 2013 Lanzhou University, Sc.B. (Applied Chemistry)

Work experience

August 2019 - now Jiangxi Science and Technology Lecturer

Field of investigation

1. Biological fluorescence sensing

2. Design of pro-oxidation anticancer drugs

Main scientific research achievements

The research primarily focuses on the fluorescence detection of various enzymes in living organisms and the design of small molecule pro-oxidant anticancer drugs. In recent years, as the project leader, I have led one National Natural Science Foundation project, completed one Jiangxi Provincial Natural Science Foundation project, one Jiangxi Provincial Department of Education Science and Technology project, and one university-level teaching reform project. As the first author or corresponding author, I have published multiple SCI papers in journals such as Free Radical Bio. Med., Talanta, J.Agr Food Chem., Bioorgan. Chem., Dyes Pigments.

Mainly Represents Academic Works/Papers/Patents

(1) Yuan Ji*, Xiaozhen Zou, Dingguo Chen, Shiran Sun, Shouzhi Pu*, Developing a julolidine-based fluorescent probe with high sensitivity for detection of nitroreductase in living cells and zebrafish, Dyes and Pigments, 2024, 226, 112115.

(2) Dingguo Chen, Yuan Ji*, Shiran Sun, Shouzhi Pu*, A turn-on fluorescence probe for imaging tyrosinase at the wound site in broken tail of zebrafish, Bioorganic Chemistry, 2024, 146, 107298.

(3) Yadan Huo, Yuan Ji*, Dingguo Chen, Shouzhi Pu*, Fast responding of mitochondrial HClO using a coumarin-based fluorescent probe in living cells and zebrafish, Dyes and Pigments, 2023, 209, 110940.

(4) Yuan Ji, Fang Dai, Shuai Yan, Jing-Yang Shi, Bo Zhou*, Identification of catechol-type diphenylbutadiene as a tyrosinase-activated pro-oxidative chemosensitizer against melanoma A375cells via glutathione S-transferase inhibition, Journal of Agricultural and Food Chemistry, 2019, 67, 9060-9069.

(5) Yuan Ji, Fang Dai, Bo Zhou*, Developing a julolidine-fluorescein-based hybrid as a highly sensitive fluorescent probe for sensing and bioimaging cysteine in living cells, Talanta, 2019, 197, 631-637.